And the WINE PRESS was trodden outside the city,
When grapes were ready, and wine was to be made, this was the way it was done. It was a messy process of putting the grapes in a vat and stomping the juice out of them. Because of the mess, the wine press usually was outside the city near the vineyards.
However, symbolically, Christ was crucified outside the city (Hebrews 13:12), and His Blood flowed as the grape juice. It is fitting that the final judgment of the world would begin outside the city.
Some commentators say this "wine press" judgment is for Jews only. They refer to what John had written earlier, "He came to his own, and those who were His own did not receive Him." (John 1:9-11-13).
and BLOOD came out from the WINE PRESS,
This fulfills the truth given to Noah (Genesis 9:6-7), "Whoever sheds man's blood (Christ's blood), by man (Son of Man) his blood shall be shed, for in the image of God He made man."
up to the horses' bridles,
This is difficult to interpret. It may be both literal and figurative. We could interpret Revelation 19:13 that the BLOOD stain on Christ's robe came up as high as the bridle as He sat on the white horse (Revelation 19:11).
for a distance of two hundred miles.
Many scholars believe this location is Israel with the center at HarMagedon (Revelation 16:16). They see the 200 million armies of horsemen of Revelation 9:16 merging into this 200 mile area. This may be. However, Christ and true believers have always had a spiritual battle (Ephesians 6:10-12-20). This may be a spiritual zone around Jerusalem with heavy demonic activity. What we have in this verse then is a response to the sixth trumpet - "Release the four angels who are bound at the great river Euphrates" (Revelation 9:14).